The University of Texas-Pan American
Environmental Health and Safety
October 24, 2016

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Institutional Radiation and Biosafety Safety Committee (IRBC)

The Institutional Radiation and Biosafety Committee (IRBC) reviews, approves, and oversees all research, clinical and educational activities involving the use of radioactive materials and radiation producing devices, and infectious biological materials and recombinant DNA at the University of Texas Pan American . This process provides guidelines that ensure appropriate procedures; equipment, facilities, and training are adequate in conjunction with the risk.

IRBC Guidelines

IRBC Membership


Any use of microbiological/infectious agents and/or recombinant DNA molecules in research must be reviewed and approved or exempted by the Institutional Radiation and Biosafety Committee (IRBC) before the procedure is initiated. The CDC/NIH manual entitled Biosafety in Microbiological and Biomedical Laboratories (BMBL) 4th Edition contains safe practices and laboratory requirements for research using microbiological agents. The NIH Guidelines for Research Involving Recombinant DNA Moleculescontains requirements for protocol review and safe practices for work involving rDNA. The procedures are outlined in the following document.

Protocol Review Procedures for the use of Infectious Agents
Protocol Review Procedures for the use of Infectious substances


Determine what biosafety level the protocol calls for (BSL- 1, 2, or 3).

Microbiological agents classified as BSL-1 are exempt from committee review. rDNA molecules referenced in Section III-F referenced in the Guidelines for Research Involving Recombinant DNA Molecules are also exempt from committee review.- Exempt rDNA molecules.

Assistance with determining your biosafety level can be had by contacting EH&S.

Required Materials:

1. Completed Application for the use of rDNA or infectious agents form
2. A copy of the research protocol which should include practices to ensure safety and health in the laboratory.
3. Copies or citations of any relevant articles

IRBC Meeting Date:

The IRBC meets on a quarterly basis .

Submission Deadline:

14 days prior to facilitate review and preparation. We will work with investigators to meet any and all grant deadlines whenever feasible.

Obtain Forms and Submit to:

Department of Environmental Health & Safety, Lamar 1.202

Once Approved:

Protocols will be reviewed on an annual basis.

Changes in Methods, Microbiological Agent / RDNS, or Personnel:

Apply by memo referencing the Institutional Radiation and Biosafety Biosafety Committee registration number. If changes are extensive, include a new set of forms.

Important Notice to Principal Investigator Applicants:

The Principal Investigator is the individual who submits the application to employ biological agents or recombinant DNA in his or her work. This individual is responsible for adherence to all guidelines and regulations. The Principal Investigator is also fully responsible for the safe use of such agents by themselves and those under his or her direction. Other specific responsibilities of the Principal Investigator are described in the UTPA Biological Safety Manual and HOP policies.

Radiation Safety

Protocol Review Procedures for the Use of Radioactive Materials
Application for the use of Radioactive Materials


Office of Research Administration and Office of Research and Sponsored Projects


Environmental Health and Safety Council


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